We created a plugin for Microsoft Expression Encoder that publishes videos to YouTube. While YouTube has great upload features, we tend to do our final encoding in Expression Encoder and this plugin has been useful in removing a few steps from the process of uploading videos.
Update: You can now download the installer from the Microsoft Expression gallery.
It's being released under the Creative Commons Attribution-No Derivs 3.0 License so feel free to share it.
There is a Donate button in there if you feel generous, but mainly I hope you find this utility useful and I look forward to any feedback.